Search for people, departments, or email addresses.
Will T Wipke
Professor Emeritus
831-459-2397 (office)
831-459-4002 (dept office)
831-459-2935 (Fax)
Physical & Biological Sciences Division
Chemistry & Biochemistry Department
Professor Emeritus
Faculty
Biomolecular Science & Engineering
Emeriti
Chemistry
Physical Sciences Building
340
Physical Sciences Building 340
by appointment
Chemistry
Post Doc, Harvard, E.J. Corey
Ph.D., UC Berkeley, Bill Dauben
B.S., University of Missouri, Columbia
Molecular engineering for drug discovery, computational high-throughput screen QSAR; virtual library design; improving cancer chemotherapy
Todd Wipke is a computational chemist, primarily interested in computer-assisted design of drugs, molecular engineering, and expert systems in organic chemistry. He is imparting to the computer strategies of construction, knowledge of chemical transformations, and knowledge of how drugs bind to proteins. This work has useful application in the design and synthesis of new drugs for AIDS, breast cancer, and inflammation, and synthesis of new catalysts and materials. His group collaborates with the pharmaceutical industry for the synthesis and testing of candidate molecules.
- B. B. Goldman, W. T. Wipke, "QSD Quadratic Shape Descriptors .2. Molecular Docking Using Quadratic Shape Descriptors (QSDock)", Proteins 1999.
- B. B. Goldman, W. T. Wipke, "QSD Quadratic Shape Descriptors .1. Rapid Superposition of Dissimilar Molecules using Geometrically Invariant Surface Descriptors," J. Chem. Inf. Comput. Sci., 39, 1999.
- J. Lawton, M. Tudor, W. T. Wipke, "The Basic Shape Topology of Protein Interfaces" in Rational Drug Design: Novel Methodology and Practical Application, ed. by A. Parrill, American Chemical Society, Washington, DC, 1999, Symposium Series.
- G. B. Fisher, J. J. Juarez-Brambila, C. T. Goralski, W. T. Wipke, and B. Singaram, "Novel Conversion of Aldehydes to Boronic Esters. Simultaneous IGOR2 Computer Generation and Experimental Observation of an Unusual Rearrangement of alpha-Aminoboranes," J. Am. Chem. Soc. 115, 440, 1993
- W. T. Wipke and M. A. Hahn, "Analogy and Intelligence in Molecular Model Building," in Artificial Intelligence Applications in Chemistry, ed. by T. Pierce and B. Hohne (American Chemical Society, Washington, DC, 1986), Symposium Series no. 306, pp. 136
This campus directory is the property of the University of California at Santa Cruz. To protect the privacy of individuals listed herein, in accordance with the State of California Information Practices Act, this directory may not be used, rented, distributed, or sold for commercial purposes. For more details, please see the university guidelines for assuring privacy of personal information in mailing lists and telephone directories. If you have any questions please contact the ITS Support Center.