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Baskin School of Engineering
Genomics Institute
Postdoctoral Scholar
Staff
Biomolecular Engineering
Postdoctoral Scholar
Biomedical Sciences
Floor 4
Genomics Institute
Research Interests:
• Human stem-cell derived brain organoids
• in vitro models of mesoscopic-level neural systems
• Synaptic changes in neurodevelopmental disorders
• Interactions between cell types on neural circuit formation and maintenance
2022-2023 UC Santa Cruz Chancellor's Postdoctoral Fellowship
2021-2024 IRACDA Postdoctoral Fellowship - UCSC Institute for the Biology of Stem Cells
2017 National Science Foundation, GRFP Honorable Mention
2016 Sheridan Center for Teaching and Learning, Level I Certification
2015-2018 Joukowsky Presidential Fellowship
2013 Summa Cum Laude Graduate - Lehigh University
2013 Lehigh University Biological Sciences Departmental Honors Recipient
2011-2013 Lehigh University Biological Sciences Research Grant Recipient
Seminars and Guest Lectures:
2019, 2018 & 2017 Brown Neuroscience Graduate Student Seminar Series, Speaker
2018 Brown Neuroscience Graduate & NIH-Graduate-Partnership Triennial Retreat, Data Blitz Presenter 2018 Neuroscience Graduate Program Annual Retreat, Invited Student Speaker
2017 Neurobiology of Learning and Memory, Brown University, Guest Lecture
2015 Department of Biological Sciences Seminar Series, Lehigh University, Invited Speaker
2019, 2018 & 2017 Brown Neuroscience Graduate Student Seminar Series, Speaker
2018 Brown Neuroscience Graduate & NIH-Graduate-Partnership Triennial Retreat, Data Blitz Presenter 2018 Neuroscience Graduate Program Annual Retreat, Invited Student Speaker
2017 Neurobiology of Learning and Memory, Brown University, Guest Lecture
2015 Department of Biological Sciences Seminar Series, Lehigh University, Invited Speaker
Selected Posters:
Cold Spring Harbor Labs: Development and 3D Modeling of the Human Brain
2019 Sevetson J, Hoffman-Kim D, "Emergent Oscillatory Dynamics in Primary Cortical Microtissues"
Cell Symposia: Engineering Organoids and Organs
2019 Sevetson J, Hoffman-Kim D, "Local network activity develops in primary rodent cortical
microtissues"
Society for Neuroscience Annual Meeting
2019 McLaughlin RM, Sevetson J, Livi LL, Hoffman-Kim D, “Exploring the effects of oxygen-glucose deprivation in a 3D cortical microtissue model”
2017 Atherton E, Sevetson J, Hoffman-Kim D, Borton D, “Self-assembled neural microtissue as a relevant,
reliable, and high throughput in vitro model of the device-tissue interface”
2017 Sevetson J, Haas J. “Calcium-dependent mechanisms underlying long-term depression of electrical
synapses in the thalamic reticular nucleus”
2016 Boutin M, Sevetson J, Kramer L, Hoffman-Kim D, “Understanding neurovascular endothelial cell
migration using in vitro three-dimensional models”
2015 Sevetson J, Haas J, “Mechanisms of long-term depression at electrical synapses in the TRN”
2014 Sevetson J, Haas J, “Common and uncommon mechanisms of LTD at electrical synapses in the TRN” 2014 Sevetson J, Haas J, “Asymmetry of electrical synapses: evidence and impact in small networks”
Scholarly Publications:
Sevetson J, Theyel B, Hoffman-Kim D (2021) Cortical spheroids display oscillatory network dynamics. Lab on a Chip, 21, 4586-4595. doi: 10.1039/D1LC00737H
Sevetson, J, Fittro, S, Heckman, E, & Haas, JS (2017). A calcium-dependent pathway underlies activity-dependent plasticity of electrical synapses in the thalamic reticular nucleus. J Physiol, 595(13), 4417-4430. doi: 10.1113/JP274049.
Sevetson J, Haas JS (2015) Asymmetry and modulation of spike timing in electrically coupled neurons. J Neurophysiol. 113(6):1743-51. doi: 10.1152/jn.00843.2014.
SciComm Publications:
“Taking the Bias out of Pain Diagnosis,” Scientific American - Jul 2019
“From the bench to the United Nations: a semi-unexpected journey,” Carney Institute for Brain Science Blog - May 2019
“Blood Tests for Brain Diseases,” TechnologyNetworks - Mar 2018
Research Matters Presentaiton - April 2019
https://www.youtube.com/watch?v=lM_2JB56qCk
"Using Minibrains to Study Brain Injury"
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