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Physical & Biological Sciences Division
Chemistry & Biochemistry Department
Distinguished Professor
Faculty
Biomolecular Science & Engineering
Regular Faculty
Chemistry
Biomedical Sciences
Biophysics
Biochemistry
Physical Sciences Building
256
Physical Sciences Bldg 256 (Office)
Physical Sciences Bldg 265 (Lab)
by appointment
Chemistry
B.S., California State University, Los Angeles
Ph.D., Cornell University
Postdoc, Cornell University
Electron paramagnetic resonance; nuclear magnetic resonance, protein structure, prion and related neurodegenerative diseases
We use biophysical methods to study neurological proteins, their cofactors and how misregulation contributes to disease.
- 1986-88 National Institutes of Health Postdoctoral Fellow
- 1993 Van't Hoff Lectureship, Royal Netherlands Academy of Arts and Sciences
- 2002 UCSC Excellence in Teaching Award
- 2005 Commencement Keynote Speaker, Crown College
- 2010 Fellow, American Association for the Advancement of Science
- 2012 Silver Medal for Biology and Medicine, International EPR Society
- 2013 Distinguished Professor, Chemistry & Biochemistry
- 2016 UCSC Excellence in Teaching Award
- 2017-18 Division of Physical and Biological Sciences Outstanding Faculty Award
- Schilling KM, Jorwal P, Ubilla-Rodriguez NC, Assafa TE, Gatdula JRP, Vultaggio JS, Harris DA, Millhauser GL. N-glycosylation is a potent regulator of prion protein neurotoxicity. Journal of Biological Chemistry 2023 299 105101.
- Guo X, Schmiege P, Assafa TE, Wang R, Xu Y, Donnelly L, Fine M, Ni X, Jiang J, Millhauser G, Feng L, Li X. Structure and mechanism of human cystine exporter cystinosin. 2022 Cell 185(20):3739-3752.
- Foley AR, Roseman GP, Chan K, Smart A, Finn TS, Yang K, Lokey RS, Millhauser GL, Raskatov JA. Evidence for aggregation-independent, PrPC-mediated Aβ cellular internalization Proc Natl Acad Sci USA 2020 117:28625-28631
- Daniel Oliver, Robert Fairlie, Glenn Millhauser, Randa Roland Minority student and teaching assistant interactions in STEM Economics of Education Review 83 2021, 102125
- Yu J, Gimenez LE, Hernandez CC, Wu Y, Wein AH, Han GW, McClary K, Mittal SR, Burdsall K, Stauch B, Wu L, Stevens SN, Peisley A, Williams SY, Chen V, Millhauser GL, Zhao S, Cone RD, Stevens RC. Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding. Science. 2020 368(6489):428-433.
- Schilling KM, Tao L, Wu B, Kiblen JTM, Ubilla-Rodriguez NC, Pushie MJ, Britt RD, Roseman GP, Harris DA, Millhauser GL. Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein are Essential for Copper Coordination and Neuroprotective Self-Regulation. J Mol Biol. 2020 May 28:S0022-2836(20)30369-7
- Wu B, McDonald AJ, Markham K, Rich CB, McHugh KP, Tatzelt J, Colby DW, Millhauser GL, Harris DA. The N-terminus of the prion protein is a toxic effector regulated by the C-terminus. Elife. 2017 May 2016.
Chemistry 1A General Chemistry
Chemistry 1B General Chemistry
Chemistry 163A Physical Chemistry
Chemistry 163C Physical Chemistry
Chemistry 200B Proteins
Biochemistry 163B Biophysical Chemistry
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