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Graduate Studies Division
Molecular, Cell, & Developmental Biology Department
Postdoctoral scholar
Staff
Genetics
Cancer
Molecular, Cell, and Developmental Biology
Bioinformatics
Sinsheimer Laboratories
204
No Mailstop
Cindy is a joint Vaske lab/Childhood Cancer Data Lab postdoctoral scholar specializing in analyzing RNA splicing in bulk and single-cell RNA-seq datasets for clinically relevant signatures. Cindy received a B.S. in Neurobiology, Physiology, and Behavior from UC Davis in 2018. As an undergraduate researcher in Dr. Hwai-Jong Cheng's lab, they became interested in the impact of environmental stressors and genetics on disease. Cindy received their PhD in Molecular, Cell and Developmental Biology studying the interplay of chemical stressors and splicing factor mutations on cancer potential in an immortalized lung cell line in the lab of Dr. Angela Brooks in 2024 at UCSC. They now continue this line of work as a postdoctoral researcher, hoping to apply their findings to understand disease mechanisms and inform treatment directions.
Wet lab: Third generation (Nanopore) library prep & sequencing; Validation of RNA-seq predictions through qRT-PCR, Western blot, immunofluorescent staining; Human cell culture & microplate assay design/execution; Automated microplate wash & dispense machinery operation; Drug treatment dose-response curve generation; Protein & nucleic acid extraction
Dry lab: Short- and long-read mRNA-seq QC and transcriptome analysis (gene expression & splicing); Analysis of primary sample sequence data from public databases; Statistical analysis & plotting of transcriptome results, single-cell fluorescent data
Cindy is interested in synthesizing the results of diverse sequencing technologies and transcriptomic analyses (e.g. short-read sequencing, long-read sequencing, protein-binding, splicing analysis, differential gene expression analysis) to create a multidimensional understanding of biological pathways altered in cancer. From their research, they hope to identify potential biomarkers for clinically relevant phenotypes such as disease progression and drug resistance.
UC Santa Cruz Chemical Screening Center Seed Grant, 2023
FASEB RNA Processing in Cancer, 2nd place short talk award, 2023
QB3-UC Santa Cruz Genomics Institute Graduate Fellowship, 2018-2019
Provost’s Undergraduate Fellowship, University of California Davis, College of Biological Sciences, 2017
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